Nope. With modern frameworks you get very powerful layout systems but they tend to favor cross-device compability and responsiveness and not the kind of layout control that desktop publishing or Photoshop gives you.

Pixel perfection is very expensive and time consuming across multiple devices. Even resorting to images can be difficult due to device responsiveness. Unless we are talking about highly targeted campaigns that feature single page apps, you won't be bothering with pixel perfect designs for ALL you sites.