For example, they use it in the Photos app on macOS and in the Photos app on iOS. Their Core Data framework is an abstraction that is built on top of SQLite, and is available for application developers on iOS, macOS, etc.
Specifically about the Photos apps on macOS and iOS though, I was underwhelmed by the performance when you deal with 100,000+ pictures and videos. I don’t know if the sort of performance issues I was seeing was tied to SQLite or not though. My own solution to this has been to move away from using the Photos app on macOS all together, and to store my photos and videos in directory hierarchies instead. And to move photos and videos off of my phone as well, into the directory hierarchies on my hard drive.