I think it very much depends on how one experiences life. The two ends of that scale are largely incomprehensible to each other.
Your point about "the next Newton" is unrelated, and IMO misses the mark. It's not coincidence that Newton, Hooke, Boyle etc appeared in the same place at the same time, and it's not because there'd been a crippling shortage of randomly arranged characteristics before that. The right characteristics aren't enough, you also need the leisure to develop them (which implies material surplus) and a society that makes sufficient use of scientific discoveries to value and propagate them. Nobody would have heard of Isaac Newton if he'd been born a subsistence farmer. I'm sure lots of potential Isaac Newtons were, and in many ways that's a tragedy.