Up's primary theme was the importance of letting go of the past to focus on the future. Soul was that you don't have a divinely foretold purpose in life other than living your best life. Inside out was about recognizing the importance of negative emotions- and that while joy is good, sadness is not bad. A lot of these are heavier and more mature than you'll find in a randomly chosen piece of fiction intended for adults, but I wouldn't say they're sad so much as thought provoking.
Some of it is really bleak. I mean, a fair bit of soul is a guy realizing he wasted his life, and then died right before doing the thing he thought would give his life meaning. But like... Grappling with that feels like a really meaningful conversation to have.
edit: although I don't feel as strongly for their sequels. To some extent I find they phone some of them in...