Ask HN: Resources/Advice on filing taxes as a Sole Proprietor?

So, like many on this website I have decided to strike out on my own. Currently I am selling custom 3D printed jewelry on my website and on Etsy. It's been a great experience learning about the technology and doing direct sales, but the taxman must get his money. I was hoping to tap the wisdom of HN to see what others do.

Is it best to just hire an accountant, use software like turbotax or credit karma, or just do it myself?

I understand that I have to file 4 times a year, so would turbotax/creditkarma handle that as well?

Do I have to file different forms or at different times for income tax vs sales tax?

Any other advice or pointers on good resources for reading would be very much appreciated.