This guy has been arguing for years that it is sugar (fructose actually) that increases the "bad" LDL in your blood stream https://www.youtube.com/watch?v=dBnniua6-oM
The normal metabolic route is that excess fructose, beyond what the liver can afford to process immediately or store itself, is carried wrapped in cholesterol to fat cells to be stored.
If you take statins, excess fructose gets dumped into your bloodstream not wrapped in cholesterol, which is much worse. It causes oxidation of blood lipids, which have long been known to cause heart and circulatory problems.
Off the top of my head, I remember the "zero carb down under" channel where some are hosted, including Lustig's talks.
/r/KetoScience delves into the research, if you are so inclined.
My understanding was that other classes of medicine that reduce serum cholesterol levels have shown no effects on heart disease in clinical trials.
Vendors have eagerly sought for any hint of evidence of preventing heart disease, or anything else, for decades, and have come up empty. That does not stop physicians from prescribing statins for slightly elevated cholesterol. Pharmaceutical companies love drugs like statins that don't cure anything, so you have to take them every month, forever. They have proven very skilled at manipulating the opinions of medical doctors, e.g. scandalously in the case recent case of opioids.
Making your liver ignore signals to produce the cholesterol your body needs to function is a very bad idea, on par with irradiating your thymus gland when it becomes enlarged (which was done, and recently! Your thymus gland is part of your immune system, enlarged when it is working.)
More particularly, permanent muscle damage.