I hope that McCLIM (https://common-lisp.net/project/mcclim/) can some day fill that role, or a project that is similar to McCLIM.
I cannot imagine a better way of interacting with a computer than to have objects that can be manipulated both interactively and with Lisp code. Emacs is already close to that ideal, but I think we could do even better.
I managed to accomplish this somewhat with Lua. Designing the engine so that all the cool things like creating and equipping items, generating maps, etc. are in public APIs you can use interactively has given me a lot of power. I'm not sure if the benefits offset the maintainability tradeoff, but I'm somehow continually excited to sit down and mess around with it. Taken as a single-user experience, being the only person to understand the system and write more code, it is almost a dream come true.