This is definitely more so the case when you run your own business. I do too and I have the same feelings, so I end up working all evenings and sometimes all weekend too.
But then I get other guilts, like not spending enough time with my wife, visiting my parents, or getting enough sleep. My brain doesn't have chance to switch off and my output is probably considerably lower than if I just stopped and took a proper break from all the tech and work
This is the main reason why I'm mandating a 4-day work week for my employees. But this is balanced... I don't then want them to feel the pressure to fit that elusive 5th day into the remaining four.
The biggest hindrance to this is that the rest of society generally works 5 days. And in the web world, people want you 24/7. But we're balking against it. Eventually, I'll get down to 4 days myself :) I can feel it