An easy way to make upper boundary estimate: let’s say you use Falcon Heavy to deliver your kinetic weapon. Falcon Heavy burns around 500 tons of fuel. This is upper boundary for energy of your payload (since most of the energy goes to lifting rocket itself and air resistance). So even ultra-heavy payload of 64 tons will have way less then 0.5 kilotons of energy (TNT equivalent used for nukes). Any nuke is way beyond that.
Of course, another way to estimate is to not to be lazy and actually multiply mv^2/2. Truly massive 64 ton kinetic weapon reaching target at 7 km/s will have energy of 1.6x10^12 J. Modest 20 kiloton nuke has energy of 8.4x10^13 J. I.e. 50 times more.
Why? pick up an NEO and aim for Sydney, or wherever it needs to go. Easy, unless your settlement isn't orbital or you don't have electric propulsion.
There is infinite supply of all sizes of boulders in space that you can just grab and turn into missiles given you have sufficient level of technology.
1. Space colonies, especially remote ones (e.g. not Moon, but Mars or Titan), are strongly motivated to be maximally independent as soon as possible. Whoever leads them must think about the possibility that the supply ships stop coming, either for some temporary disruption (pandemics on Earth, cough, cough, or even a war back home), or permanently (something has gone seriously wrong on the blue planet). And imports from Earth are expensive, because they have to be lifted out of the Earth's gravitational well. This means that the colony will try to produce everything necessary in situ for good reasons; such a colony will not be easily brought to its knees by a blockade.
2. It is easy to block a colony physically, but they will still be able to communicate back to Earth and argue their cause in front of the rest of the humanity. This will undermine the will of Earthly powers to maintain the blockade.
3. We are now in a rare situation when only one nation (the U.S.) is approaching the capability to send ships to the rest of the Solar System. It is not unlike the situation when only the Portuguese mastered the carrack and were the only ones to sail regularly from Europe to India in the late 1400s. But this situation will not last and I would guess that by 2050, at least five or six sovereign entities will have the same capability. By 2100 for sure. And their political differences will be exploited. It is unlikely that all of them would decide to start a common punitive embargo against a rebel colony.
China is on their way to mars as well with Tianwen-1, India is ramping up their space program, ESA is launching their stuff with Ariane vehicle as far as Jupiter, Russians with Angara have plan for crewed moon flyby in 2029. So it is not like other nations won't have that capability soon after US and not like US has it right now or next year.
Second part is that there is still not that much of commercial gain in going to Mars, Moon or other place. Most of the money is made in LEO with satellite communications, gps, utilities. Space mining is not going to be profitable for really long time into the future. Where going to India was profitable right away if you had a ship to carry spices you were really ahead of the others. Space ship capability is just the starting point and we still have to find something that is worth enough to send those ships there, even with SpaceX reusable rockets it is still not worth to mine rare earth elements somewhere else in the solar system.
Yes it's very hard to get a soft landing on Mars, and props to any agency that can do it. We expect great things from Tianwen-1. But it's many times harder to develop a complete process to soft land 100mt there, 100 times a year.
This is the same engineering process that spanked ULA, who with a century of experience and head start, has yet to complete its commercial crew rating, plus they are single shot, not reusable.
That is a very Americanized view of how things are. Unless something goes wrong CNSA will land Tianwen-1 on Mars a week before Percy gets there. Your comment is written in a tiny timeframe where the US is actually at or near the front but looking over time this isn't the case.
And speaking of sovereignty & Spanish-Portugal colonization, I wonder what the interstellar version of the Treaty of Tordesillas is gonna look like.