Versus piping my audio through OBS as a way of using RNNoise and doing noise gating, OBS retains the original audio quality quite well and does a really good job of removing clicks/clacks/etc.

Krisp made my voice sound like I was talking through two tin cans and a string, and, at least in my environment, did not do a very good job of actually removing any of the background sounds.

I've also tried it in Discord (as it's integrated directly into Discord) and kept running into a problem of it deciding my own voice was noise and just cutting me out mid word.

They have a free tier (gives you 120min/week of noise cancelling), so anyone looking to try it definitely worth using that first. I'd suggest turning on audio monitoring in some headphones and listening to yourself a bit though and deciding if the quality is acceptable to you.