A well cooked pot roast is not that much different from the sous vide trend that's becoming so popular.

You put the roast in a dutch oven coated in salt and pepper the same as you would with a steak and a bit of water, then you let it cook at ~200F for 4 - 8 hours.

Usually you also slow roast some onions, carrots, potatoes, etc. along with it the last little while.

Then make a gravy from the drippings.

The gravy is good on the meat, but it's more for the vegetables. The meat is delicious in its own right.