Being sedentary is not very good on your body, muscles atrophy, joints become stiff, your body tires easier and from there it’s a downward slope. If you have enough physical activity then you need not worry about this but there are other factors. Like muscles all other faculties atrophy as well without use. Physical activity is good for the brain as well.

I think of the computer as a tool at the end of the day. It is a very powerful tool which has radically changed how we do things but it’s still a tool.

Lastly it’s healthy to take a break from whatever main activity, whatever that is - could be being on the computer all the time programming or playing games - so that a different perspective sweeps in.