"Allison was hoping to be published by one of the leading peer-reviewed research journals. But nobody at Cell or Nature or any of the A-list, peer-reviewed journals was willing to publish the findings of this junior academic from Smithville, Texas. “Finally, I ended up publishing the results in a new journal called The Journal of Immunology.” It wasn’t Science or the New England Journal of Medicine, but it was in print, and in the world.
“At the end of the paper, I said, ‘This might be the cell antigen receptor, and here are the reasons why I think that it is the T-cell antigen receptor,’ and I just listed it out, all the reasons.” It was a bold announcement regarding the biggest topic in immunology. “And nobody noticed it,” Allison says. “Except in one lab.”"
https://www.wired.com/story/meet-jim-allison-the-texan-who-j...
So you really need to publish the marginal stuff to make sure the breakthrough stuff gets published as well.