What?
I can’t make sense of what you’re even trying to say:
1. That the mechanism of harm is different tells us nothing about the relative risks. I don’t OD on cars, but cars are riskier than Asprin.
2. You can have long term negative impacts from, eg, vaccine carriers. (Which is why we stopped using some....)
3. Overdosing a live virus vaccine happens all the time, the result being you get the illness. A flu shot can kill you by giving you a deadly flu.