The important to thing to realize about Pandermix was that the rate of people impact was so small that even if we followed 50k phase 3 participants over 10 years, we wouldn't have uncovered the issue.

The narcolepsy issue was never going to be uncovered before it was rolled out large scale.

According to https://journals.plos.org/plosone/article?id=10.1371%2Fjourn...

the onset judged by "first contact to health care" was much earlier.