1. Save your progress to disk periodically -- for a genetic algorithm, that will be the seeds passed to the next generation. That way, you'll only lose one generation if you need to unplug your box. As a programmer who does any amount of research, this is a superpower. Godliness is achieved when you automatically commit this data, summary metrics, and the code that generates it into a git repo.
2. Invest in a UPS. If you need to do a project that will take longer than your UPS will last, you can just move the box & UPS onto another circuit.
But, yes, be careful with electricity. Lessons from my grandpa, who survived all of his live-circuit edits and died of lung cancer:
3. Wear rubber-soled boots.
4. Keep one hand behind your back.
5. Use rubber-handled tools and do not touch the metal bits.
6. If a ladder is necessary, it should be non-conductive.
7. Equip your child with a 2x4 and give them the instructions to pry you away from the source of electricity with that, and to not touch you under any circumstances.