This is talking about the SARS-CoV-2 VOC 202012/01 variant [0], aka B.1.1.7., aka carrying the N501Y mutation.
No news here, other than confirmed spread to Japan.
[0] https://www.cdc.gov/coronavirus/2019-ncov/more/scientific-br...
This is talking about the SARS-CoV-2 VOC 202012/01 variant [0], aka B.1.1.7., aka carrying the N501Y mutation.
No news here, other than confirmed spread to Japan.
[0] https://www.cdc.gov/coronavirus/2019-ncov/more/scientific-br...
https://nextstrain.org/groups/neherlab/ncov/S.N501?animate=2...
N50Y has also a similar antibody neutralization profile as the non-mutated version.
Of course, these data refer to the mutations on their own, not together.
More on the deletion (on its own, again): while it is supposedly tied to a faster entry into the cells (twice as efficient in experimental assays), it look like it has lower fitness in absence of an ongoing immune response (it would lower in presence - but not disappear - in the immunocompromised patient it was first found into between treatments with convalescent serum).