Maybe I'm just grumpy, but... if you send me a cold email, I'll either respond or delete it. Then, if the original didn't have an "unsubscribe" link, plus you follow up on it, I'll tell gmail to block you.
However, one thing people don’t do often enough is follow up when the other person has expressed interest. This kind of followup is usually welcome, as inertia and distraction lead to things not happening. This is especially true in commercial context. Eg someone may express strong interest in buying, get busy, drift off, then enthusiastically buy when you ping them a bit later.
I gave advice to many people who cold emailed me.
But in my personal experience, most cold emails I wrote wouldn't lead to much, because my inquiries were too specific.