That’s what I would probably do since it’s more efficient and simpler. No need for a compilation step or an interpreter. No need to trust the (likely complex) webassembly runtime to be bug free.
Edit: most responses are being made under the assumption that seccomp is the same as seccomp-bpf. The two are different and designed for different use cases. For example it is not possible to run a wasm JIT entirely under seccomp but is possible under seccomp-bpf. Seccomp was specifically designed for the use case described in this article by Shopify. You can read more about the differences here https://en.wikipedia.org/wiki/Seccomp