you cannot make the argument that unforseeable effects are patently bad. You're contradicting your terms, and arguing that you have an inkling that it would be bad, rather than, possibly, good.
Yeah, some, perhaps even many, risks get you sunk. On the other side of the coin, nothing we discuss here would exist if people didn't take risks with their businesses.
The world would be so different if no-one took risks. I daresay we wouldn't be making tools, have a knowledge of agriculture, or even have spread out of Africa.