VcXsrv binds to localhost by default, so unless you already have malware on your system the added risk is quite small I'd say.
It used to be possible to easily scan what sites are running locally, even if js code was from a public website. [0]
If you're talking about using that exploit to allow access to the victim's machine from the internet: that won't work because listening interface for the x11 server is localhost, not the LAN interface.