Sure. We're not talking about Facebook here, they'll be fine. We're talking about random sites and apps. How many apps on the Play/App Store actually implement differential pricing by region?
This cannot be an afterthought—it must be the central question all advertising skeptics must start with.
If ad companies manage to set up international ad networks that show relevant ads to the user according to their home country and interests, I wonder if all that effort and hard work couldn't have instead be spent building a platform for collecting payment internationally