And like u/strogonoff, I also disable line numbers, but that's just personal preference of course. For vim newbies, relative lines might also be worth checking out: "set relativenumber".
One thing that really annoys me is :Wq or :Q not being commands. Or typing only Q because you didn't hit the : and accidentally entering ex mode. Or hitting F1 instead of escape. I can recommend:
command Wq wq
command WQ wq
command W w
command Q q
nnoremap Q <nop>
map <F1> <Esc>
imap <F1> <Esc>
Or for the non-newbie that has the 'too many terminals' problem, "set title" will give your terminals more useful titles. There are a bunch more things, of course, but these are the lines in my vimrc that I think are useful to most people.