The reproducible part is that they can consistently fold proteins - which they can.
The fact that they're not telling anybody else how they did it stops it from being public science, but doesn't stop it from being science.
The fact that they're not telling anybody else how they did it stops it from being public science, but doesn't stop it from being science.
Reproducible: Can it be done again?
Replicable: Can someone else do it?
AF2 appears to be reproducible, but not yet replicable.
https://phys.org/news/2019-05-replicability-science.html#:~:....
Why not? I don't see a blocker except for the money to create a team and the computational resources. I think AlphaGo/Zero was harder to replicate than this, still Leela's team managed to get it working.