Definitely. At our company our network provider decided that it's better for us to use ipv6 from now on. For one day the customer support couldn't figure out what was wrong with our network. They even suggested that the recent heavy rain might have damaged the lines. Finally after a few struggles they mentioned in one sentence that they switched our region to ipv6 only, and that was when we, the customer, realized what's wrong. And obviously, we have a business plan. So that was one day of work without any internet.