"Wouldn't it seem more likely that California latinos statistically disregard health officials advice" - No. For example: a lot of communities have intergenerational families living in close proximity due to lack of affordable housing, jobs, redlining, etc. Having many people living closer together explains being "most impacted" as well as (obviously better than but hey I'm being magnanimous) your thesis that people are choosing to "disregard advice". Just... no.
I could say "Alaskans are disproportionately affected by testicular cancer", because their per capita rate of it is higher than any other state. But it has nothing to do with being Alaskan - they have a totally normal rate of testicular cancer - it is just because a higher percentage of men live there than anywhere else in the US.
And, her next tweet in that thread is her celebrating keeping playgrounds open. Yes, children need to play - but maybe they can spread covid there?
Having many kids is part of it too.