All repo settings will look to local repo so we'd have no dependency problem or version creep if we need to install an additional package.
Didn't completely think how to handle the occasional emergency update though.
Also, we need to compile in some packages. Hope they won't break. High performance stuff needs optimized/customized compilations.
I just want to add: Hope that the packages in CentOS stream won't end up too cutting edge for the scientific software community. These communities move slow due to stability requirements. We'll certainly see but it might be another potential problem.
I think HN is the only place where you can casually provide feedback and get answers about an OS project from one of the core people in it. Fun!
Glad to meet you, BTW.