>I'm not sure anything can protect against a targeted attack from a nation-state.
hardware airgap can go a long way
hardware airgap can go a long way
A great book on Russian, state-backed hacking group was by a senior Wired writer, Andy Greenberg, called "Sandworm" [0]
[0] https://www.amazon.com/Sandworm-Cyberwar-Kremlins-Dangerous-...
One of the most common is interdiction of computers in shipping and installation of hardware implants.