For users who have optimized for the current pricing structure, this is an insane switch, to give you an idea I just did the calculation for our AppEngine costs. Ouch...

We currently pay about $0.60 a day, so $18 a month

On the new system we have 25 instances on average so 24 * 25 * 0.08 = $48 a day or $1440 a month, even with reserved instances this is $900 a month, a x50 increase....

We do thousands of small requests, optimized for low CPU usage and not instance count, guess its time to move.