I doubt people will talk about Covid-19 much at all by the end of the century.
The 1918 flu was much, much worse in total number of deaths, and even worse when you consider how many fewer people existed at that time, and it killed people in the prime of their lives. And by the year 2000 very few people knew about it at all.
In contrast, the 2020 pandemic is presently not sharing the spotlight. Maybe something of comparable impact will happen. Or maybe it'll be forgotten regardless. But I don't know that the 1918 pandemic's status is all that illustrative.
I suspect that COVID-19 will replace the Spanish Flu as the "pandemic everyone talks about when there's a pandemic concern," but this is the sort of mention that requires explanation because it's not really part of the expected repertoire of history the same way the Black Death is.
With this latest surge per-capita deaths from covid19 just passed the low end of the 1968 flu estimates.
It was pretty bad. The flu has all the long term complications for some people that covid does - the lung problems, heart swelling, brain problems, etc.
I talk to people who were alive in 1968. It just wasn't really on anyone's radar. Rarely made headlines in the U.S.