There was (is?) a duopoly of manufacturers for estradiol valerate: Par and Perrigo. [0] Perrigo stopped manufacturing, only disclosing issues with "shortages of an inactive component" to the FDA and refusing further comment. Par said their supplier for the API pulled out, and had to rework their supply chain.
I eventually managed to track down a trans-run compounding pharmacy that had apparently stockpiled the stuff (so grateful to my community!) but it was a rough time and I'm glad my ex came through for me. Detransitioning is harrowing, I speak from experience.
0. http://www.ridgepoliticalreviews.com/all-articles/no-country...
Really? Do you have any basis for saying this? For many people, going without meds is like going without glasses--you may be able to walk around without your glasses, but you're not functioning the way you want to.
https://www.newyorker.com/magazine/2019/04/08/the-challenge-...