Face masks considerably reduce Covid-19 cases in Germany
pnas.org
pnas.org
It bases its conclusion on a few hundred cases in the German city of Jena back in April. In fact, the authors themselves apply the same analysis to other cities over the same time period (figure S15 in the supplementary material) and those plots show hardly any effect.
However... if a paper claims to support X and the paper is bad, then that does not mean that X is incorrect. And given government advice around the world, it seems pretty clear that masks are understood to do more good than harm.
That's an appeal to authority. It also doesn't mean it's incorrect but it's not evidence of anything.
Especially in a case such as this an appeal to authority can be useful, as there is a big bad-faith storm of "discussion" surrounding the subject that really isn't doing anyone any favours.
With limited knowledge, I'm inclined to go along with measures that are low cost and have a plausible explanation wrt. effectiveness. That being said, if the mask situation has shown us anything, it's that the authorities are neither trustworthy nor competent.
How did the mask situation show that authorities are not trustworthy or competent?
That said, let me double down and state that I wholeheartedly recommend using the scientific consensus as a prior for your opinion on any given topic. :)
Otherwise going to a doctor for a sickness, or hiring an engineer to build a house would be fallacious as well.
(And give the amounts of PhDs that are incompetent or just crazy in areas they should know better is astounding but I digress)
Don't trust anyone but yourself.
With that said, the medical professionals telling people to wear masks always say in addition to distancing and hygiene.
1) https://news.ycombinator.com/item?id=25301380
2) The Swiss cheese model of how defences, barriers, and safeguards may be penetrated by an accident trajectory (see the figure):
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1117770/
https://www.wsj.com/articles/how-the-swiss-cheese-model-can-...
They use a 7-day rolling average and general consensus is that covid has a 3-14 day incubation period. Combining these two would indicate that the mask's effect should be gradually becoming stronger starting ~4days after introducing and reaching peak effect after 21 days in the graph. The graphs show a strong effect after 4 days and remain constant after that. Does that undermine the conclusion or am I seeing this wrong?
They use a linear regression while infection is an exponential process in my understanding, doesn't this undermine the regression?
Until sometime in March or April, government advice all around the western world was that masks in community settings are ineffective and possibly dangerous (due to improper handling).
Usually when these agencies change position or announce a new position, the decision is accompanied by a properly referenced whitepaper that lays out the evidence for the new position. This hasn't happened here.
Jena is a single data point supporting the effectivity of masks (there could be indirect effects at work as well, i.e. people better grasping the severity of the situation). The sophisticated average that they use as comparison makes it appear to carry more confidence than it does.
And that is why post-hoc hypotheses aren’t valid. It does not, however, invalidate this study.
Incidentally, I found somebody who prayed for all cities except Weimar and Jena, so this neutralises your anonymous friend’s prayer.
I agree on this. Can you point to where they announced the study on April 6th or before? Or did the decide to look at Jena only after the data was available? How is that not a post-hoc hypothesis?
Of course, both general hypotheses of masks and prayer predate Covid19.
> It does not, however, invalidate this study. No. The study contributes a single data point in favor of masks, but is not very convincing (in that the authors did not look deep into contradictions and alternative explanations) and of course not conclusive as the bad title makes it appear.
You’re right that it’s a single data point (though with a strong effect size). And, being an observational study, it simply can’t exclude all confounding factors, and will never approach the strength that a controlled study could. Nobody is disputing that. Interpretation of observational studies always needs to be tempered by the reality that it’s impossible to control for all confounders.
But within these given constraints the study essentially provides as strong evidence as could reasonably be expected (unless the study has a flaw that I’m overlooking and which, as far as I know, hasn’t yet been pointed out elsewhere). Their design of the synthetic control is statistically sound and controls for a very large number of reasonable confounders. And, contrary to the claim in the comment I’m replying to, data from other cities does not invalidate the study’s findings. As far as I can see, the study’s inadequacies are all due to external circumstances and not because it’s a bad study.
When the situation gets worse then not only the top smartest people but also larger masses begin to take it more seriously to protect themselves, keeping distance, and omitting trips and reducing contacts.
This obviously doesn't apply to careless people or "non-believers" but they wouldn't be much affected by regulations either. So there's always (hopefully) a minority of the population where the virus can spread more easily but once the majority successfully does react it will show positively in the growth curves within about 10 days.
Coincidentally this is also the same time where governments impose strong recommendations or even enforce counter measures. Mandatory shutdowns of cafes and restaurants might seem an effective ordinance but the truth is that by that time most people already refrain from going to crowded places such as cafes and restaurants. And usually there's at least a few points of empirical data from neighbouring countries that those same counter-measures alone won't help limiting the growth if the people themselves aren't in it. It only takes one mask-wearing country to not recover from infection growth in order to make it questionable whether masks help much at all.
Keeping distance seems much more effective than masks. In reality, I've seen that when masks became common place people partially reverted back to flocking together and not respecting a good radius of personal space anymore. Masks probably won't hurt if you need to be close to other people but it would be much, much better to keep the distance in the first place.
I've noticed this when visiting the shops daily when I get my lunch. Before mask were mandated, almost everyone kept each other at a distance. Since mask wearing people have barely bothered.
I've mentioned this to friends on my discord server. Some are from Europe or elsewhere in the UK and they have noticed the same.
> When the situation gets worse then not only the top smartest people but also larger masses begin to take it more seriously to protect themselves, keeping distance, and omitting trips and reducing contacts.
Also it's not only smart people who don't get infected. Think about anyone with kids , anyone doing a job in which they face more people.
As it happens the UK's second wave kicked into exponential increase around mid August - the only major public health policy intervention coincident with this was mandatory mask wearing. So yeah.
1 - https://www.gov.uk/guidance/get-a-discount-with-the-eat-out-...
That’s wrong, the opposite is the case. The study controls for this by looking at a synthetic control over the same time period, which consists of other populations without mandatory mask-wearing. It’s an observational study so it can’t control for everything but it does control for seasonality, even if “seasonality” isn’t specifically mentioned in the paper.
Of course this is just my rough calculation (latest population census divided by the number of active cases), and the number is expected to improve somewhat as the amount of population with antibodies increases, but I'm pretty sure masks help.
The authors compute a sophisticated average of German cities and compare the weighted number of positive SARS-CoV-2 tests to the city of Jena for a timespan of one month starting just before masks became obligatory there (6th April). Masks did not become obligatory elsewhere and roughly around the mask obligation new positive cases drastically reduced in Jena whereas the weighted average shows no such effect.
EDIT: moved my doubts in the study into extra comment.
If you think the summary is wrong, please leave a comment pointing out in which way, after downvoting.
I have to challenge this assessment from the article. Masks did become mandatory elsewhere. Mostly in targeted spots in the cities such as the zeil in Frankfurt and Potsdamer platz in Berlin and I can tell you that it is met with strict enforcement and that people are adhering to the rule ardently with very few exceptions. The article and much of the science leaves much to be desired.
It is my opinion that the “all or nothing” pro mask people are actually obstructing the science. Their intolerance to confront or question evidence that is contradictory or unexplained anomalies in the data such as this article is dangerous to actually having the right response to covid leads to nonsensical draconian rules like the California mayor suggesting requiring wearing a mask 24 hours a day and only removing between bites when eating.
[1] https://www.msn.com/de-de/nachrichten/panorama/ab-freitag-ma...
The study does not look into other east German cities like Weimar[1] or Rostock that showed a similar drop in positive tests without mask obligations. New positive tests in Jena recently reached an all time high. [2]
On top of that it seems the study hypotheses for these papers are clearly biased towards proving a positive correlation between infections and mask use, even though one could do exactly the same kind of study in many other parts of the world where infections exploded along with increasingly expansive mask mandates. For example France and Spain, where numbers only started to go down after they went into second lockdown.
No matter what you think of mask effectiveness, cherry picking statistics is bad science, and so far that’s all I’ve seen as far as the ‘masks are effective’ studies go.
I feel like every other day there is a new study or report that refutes the study or the report I just saw from another respected institution. I'm not surprised people are frustrated at this problem. As an example, look at this study that was posted just 13 days ago on HackerNews: https://news.ycombinator.com/item?id=25159583
The Danish study is not good. They're not controlling for mask/no mask, they're controlling for suggestion to use masks (and they didn't even go back and ask "did you wear a mask or not).
In the end it seems people are more worried in publishing hastly prepared experiments/results than worrying about getting to the bottom of things.
> How can we not know based on the shear mechanics of these two entities whether this is effective?
It seems obvious to me that masks have a positive effect. A mechanical barrier is better than nothing. "Oh but influenza" Influenza and Coronaviruses are different
Doctors and Dentists don't use masks because they think it's funny or comfortable
Especially when tongue depression or other procedures might trigger a release of saliva, or make the saliva in the mouth spread. Or cough. Or sneezes.
If you were a doctor, would you be happy seeing a patient with a weird cough without masks/eye protection?
"The results could indicate a more moderate degree of protection of 15-20%" to the wearer.
"The findings are consistent with previous research. Health experts have long said a mask provides only limited protection for the person wearing it, but can dramatically reduce the risk to others if the wearer is infected, even when showing no symptoms. Preventing the spread to others is known as source control."
Now consider the following: if the "current" R number (the average of how many people are further infected by one infected person) in some environment is 1.2 that still results in the number of infected per day exponentially(!) increasing. Example: after the sequence of 10 infections with R 1.2 there are 6 infected, after the sequence of 20 -- 38, after the sequence of 30 -- 237 and after the sequence of 100 -- 82 million people infected, starting from just one. It is estimated that it takes just a few days for one sequence. Taking that number to be around 3.6 (it doesn't have to be that number, it's just to take some convenient number as an illustration) means that 100 sequences can be imagined as one year. So 82 million in one year.
Now if every wearer is protected only 20%, it can appear to the wearer who doesn't understand math that he should not wear it. However, reducing current R number from 1.2 to 1 means that the number of infected per day doesn't increase at all but remains constant. Example: starting with 1 infected, after the sequence of 100 there are just 100 infected. Using the same convenient number, after one year, still just 100 infected.
That, in turn, means that if everybody wears it, everybody wins: allowing exponential increase of infected will result in everybody becoming infected, whereas the constant number of daily infected could guarantee that most don't become infected before they can be vaccinated.
Not to mention that if the number of infected per day can be kept constant some other kinds of measures (lockdowns with closures, bad for economy) could be completely avoided, especially if it is achieved at some low level. Which means that it can be of immense benefit to the wearer to wear the mask as much as possible even if he increased his own direct protection in some specific situation for mere 20%! Moreover, the benefits are dependent on most others also wearing the mask! If he's doing that alone, than it's in vain -- he alone can't change R for the whole population: his highest interest is to convince others to do the same.
Being willing to understand math and to read carefully helps.
Side note, I recently read a good book that addressed why people have such a hard time with percentages. People tend to take numbers like 20% and think 0 and 80% and think certainty.
https://www.albartlett.org/presentations/arithmetic_populati...
"It's a great pleasure to be here, and to have a chance just to share with you some very simple ideas about the problems we're facing. Some of these problems are local, some are national, some are global.
They're all tied together. They're tied together by arithmetic, and the arithmetic isn't very difficult. What I hope to do is, I hope to be able to convince you that the greatest shortcoming of the human race is our inability to understand the exponential function."
That's why when some hear that R=1.2 can be catastrophic and R=1 can be fine they just switch off. And there is exactly that "only 20% percent" difference.
But many developments in nature that work against humans have exponential behavior, including the stuff that humans do.
Somebody once named the video of that Bartlett's presentation "The Most Important Video You'll Ever See" and in this case it's not a clickbait.
Edit: What's the name of the book you mention?
The paper is open access by the way.
June version: http://ftp.iza.org/dp13319.pdf
Yes yes, I know. Just let me explain.
Masks DO help prevent the range particles can travel when you breathe. I'm not arguing that. The fact is, however, they're useless in comparison to the ACTUAL champions of prevention.
And that would largely be hygiene. I'm willing to bet 99% of you reading this do not clean your fingernails properly while washing your hands. Which is fine, THAT'S how good soap is. Doing it poorly is orders of magnitude better than not doing it all.
Is the same true of masks? Absolutely not. If you don't wear a mask properly, it's useless. It gets worse with specialised gear, like the N95s. You need to be trained on how to fit, test and adjust that. Have a beard? Not gonna work. Small leak out the top? Nope, it's buggered.
You ever notice how developing nations struggle with higher infant mortality rates, caused by preventable communicative diseases like cholera? It's because they don't wash their hands with soap. Soap is literally a life saver [0]. There's a damned good chance it's saved you a nasty infection, if not your life, directly or otherwise.
It's strange to me we understand why gloves aren't effective, but somehow that logic gets lost when masks pop up. If you don't know how to stop yourself from contaminating your environment, you're really not getting anything from wearing a mask. Or gloves. Or scrubs.
China is a fantastic example of this. They just ignored the whole "human rights" problem and went straight to welding people into their own homes [1]. Highly effective. Conversely, they'd been wearing masks for a long time because of their air pollution. Clearly not very effective. (The point here is the behavior and the objective is more important than the mask).
Here's what we should be focusing our energy on:
1. Social Distancing
2. Wash your hands properly [2]
3. Coughing etiquette
4. And then, finally, PPE including masks. If you don't know how to use gloves properly, then don't waste your money (because we all seem to forget economics is also a problem to solve here).
JUST focusing on masks won't cut it. Rather focus on JUST washing your hands then. You will see a much larger return on investment there. That evidence is also irrefutable. Compare the rate of death from communicable diseases in areas where washing with soap is prevalent to areas where it is not. SARS-CoV-2 has a lipid bi-layer, so soap will destroy it.
[0]: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2587156/
[1]: https://www.cbc.ca/player/play/1703503427818
[2]: https://www.youtube.com/watch?v=xLIFT9xoWSQ the key bit here is scrape your nails against your hands when they're full of soap, so that the soap gets UNDER your nails too. Germs are tiny, and everywhere. So get em good
And as for coughing etiquette, I can’t remember when I last heard somebody cough or sneeze when out. I’m sure it happens (after all, it’s sometimes unavoidable) but it has definitely gotten much rarer. In sum, it’s a very strong claim to say that “masks are a pointless waste of time”, and almost certainly wildly off the mark.
^1 Of course hand-washing should be practiced nevertheless, because it also prevents other infections, notably GI infections. But paradoxically excessive hand-washing also has negative health implications: soap and alcohol destroy the skin’s protective layer and dry it out, and the mechanical action of hand-washing exacerbates this through abrasion, which causes micro-lesions, irritation, and increases the risk of catching infections. And unlike for mask-wearing we actually have very good evidence for this. We don’t yet know the exact consequences, but the NHS has noticed a strong uptick in dermatological conditions since the beginning of the pandemic, some of which are serious. (Here’s a publication on this: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7102542/)
https://thefederalist.com/2020/10/29/these-12-graphs-show-ma...
EDIT: I would appreciate a proper rebuttal instead of what I can only interpret as downvotes for wrongthink.
There is no information about what proportion of the populations actually wore masks, how close people actually got to each other, what the population density and degree of urbanization is, etc.
In Norway we mostly have not had strict lockdowns and have not had compulsory mask wearing until very recently and our infection rates and death rates are lower than most other countries as shown on the charts. But you need to be careful how you interpret that; Norway has a relatively low population density and a large proportion of jobs are of a type that can be done at home. So pretty much everyone who could work from home immediately did so (a lot did anyway). We also have a strong tradition of solidarity; unlike the UK 'We're all in this together!' is not just a slogan.
Our government has also been largely consistent in the advice that it has issued and, with a couple of exceptions, avoided overreacting which means that people are willing to adhere to the rules even though most are just advice and not enforceable.
Most charts from all sources, and especially things like the Federalist, should be taken with a shovel of salt; not because of what they include but because of all the information that is omitted.
>There is no information about what proportion of the populations actually wore masks
If you had scrolled a bit, you'd have seen the chart linked highlighting compliance rates: https://yougov.co.uk/topics/international/articles-reports/2...
I looked at the chart titled 'Avoiding going to work' and was bemused because I couldn't see the line for Norway, where I live. When I turned of the Asia, and US I was able to see it. It would be interesting to know the expected error of the surveys that were used to generate that because the impression I have is that vastly more than 18% of the Norwegian working population is working from home. In fact even in normal times a lot of people work from home a significant fraction of the time.
So I am still of the opinion that such charts don't tell us very much and in particular they do not tell us how much we can rely on them.
And one last point: there is a chart showing that 40% of Norwegians say that they are 'Avoiding physical contact with tourists'. What tourists? There have been essentially zero foreign tourists in Norway since March and internal tourism has practically disappeared a well so what meaning, if any, can be associated with such a statistic.
1. The article attacks a straw man, in that it suggests that masks are supposed to be a cure-all against Covid-transmission. I have not heard this seriously claimed - rather, masks are only one of a range of responses. (Indeed, by far the most important and effective reaction seems to be reducing the number of personal contacts - masks are only intended for those situations where this is not possible.)
2. Masks can only be effective where they are worn. At least in Germany, recent data suggests that most infections are taking place in private settings - where masks are not compulsory (and usually not worn). This could be used to argue both ways: either that the widespread use of masks in public has been successful in reducing infections in the public space, or that the continued widespread infection in private settings means that wearing masks in public is irrelevant. (I do not have the data to meaningfully compare these two claims.)
3. The evidence we have on the effectiveness of masks does seem to be pretty patchy, with many studies showing methodological problems and coming to different conclusions.
4. Generally, the protection effect for the wearer seems to be low or non-existent. However, while not significantly reducing inhalation of virus particles, masks do reduce droplet exhalation (and so protect others in the vicinity of the wearer). I.e., there is an indirect protection effect.
5. It seems to be true that masks are not very effective against aerosol infection (preventing this requires other measures, specifically good ventilation). However, this cannot be used to argue that masks are superfluous, as droplet infection (which masks do help with) is another important transmission vector for Sars-CoV-2.
TL;DR Masks are not a cure-all. They must be used in conjunction with other preventative measures, or they are useless. However, they are probably effective as part of such a larger package.
Germany did not wear masks on the first shutdown in spring (same as Danmark and Sweden) - the were not available and they came as the spread already went down heading summer.
As for the headline, Germany has a strict shutdown at the moment.
I've been invited to three orgies, with dates TBD ("as soon as this ('gestures around') is over", one says). So maybe we'll have an entirely newfound appreciation of touch.
Where are the "if it's not a double blind study where you isolate a variable, you haven't proven anything" people when we need them!
This effect is controlled for by the study, by comparing Jena to synthetic control groups.
Yes if only we had a second Earth.