Telsa / SpaceX / Elon - focused on ground up physics principals. They said things like, how can we make a better battery pack and will the math then work for a good EV car. They showed to their satisfaction that the answer was yes, and built from there to a degree. Their battery / powertrain work has been consistently good before any of the huge capital efforts, and the path forward was pretty well defined.
Same with their rocket engines. They iterate and qualify pretty quickly.
ITER and these folks are spending billions on what is actually ancient tech with really no realistic (I don't think) path to sustainable commercial power even theoretically in any reasonable time horizon. This is the Space Launch System approach, gear up and go on old tech.
We do need someone in a lab (Tesla / SpaceX style) iterating, and then proving out key physics / components. The problem with ITER, you CANNOT stop funding it, it's just gobbling up all the money because the number of jobs now tied to this - it's a jobs machine basically.
At spaceX it doesn't feel like their are a lot of sacred cows. These maga projects are pure sacred cow it feels like sometime. It's private / personal capital driven.