> I wonder if we can determine if this extends to proteins that aren't as keen to determining their 3D structure?
This is already happened.
"An AlphaFold prediction helped to determine the structure of a bacterial protein that Lupas’s lab has been trying to crack for years. Lupas’s team had previously collected raw X-ray diffraction data, but transforming these Rorschach-like patterns into a structure requires some information about the shape of the protein. Tricks for getting this information, as well as other prediction tools, had failed. “The model from group 427 gave us our structure in half an hour, after we had spent a decade trying everything,” Lupas says."