I've Recorded My Drug Use in an Excel Sheet for Nine Years
vice.com
vice.com
As the saying goes, you can’t manage what you can’t measure so at least he’s got that going for him.
The rat studies, while imperfect, point to neurotoxicity [1]. The longitudinal studies also show negative long term effects [2]. Even Shulgin, the man that "discovered" MDMA, advises against using more than 4 times a year [3].
[1] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1705495/
[2] https://www.ncbi.nlm.nih.gov/books/NBK56825/
[3] PIHKAL, Shulgin
My experience is far below that of the author, however in general I figured that it was safest to stick to a general list of rules. This goes for everything including alcohol. For me at least these were:
1. Don't consume anything by yourself, especially at home.
2. If you are in a sad mood or similar, think twice before taking anything. Are you doing this to avoid a problem in your life?
3. If you are to take something, make sure you understand what it is, what the dose is, and what the side effects and risks are.
4. Avoid anything with a high possibility of addiction or damage to health.
For me this has pretty much resulted in only ever trying: Alcohol, Weed (edible form preferably) and once or twice Psychadelics. Alcohol is a strange one, since it is objectively quite dangerous but very socially acceptable. In this case keeping an eye on how frequently you drink is important.
Though I've been offered coke, or MDMA or similar, I have always refused for the above reasons. Maybe it's possible these things can be safely taken / moderated, but having seen people take these and long term go off the rails, it does not seem like a worthwhile risk.
Reading articles about common drug use and watching Hollywood movies really makes me feel as if I've missed a big part of living life :( I wish I too had friends like this who would have helped me experiment and live life like this.
So, you know ... never too late if you really want to see what it's all about.
That being said, personally, I think drugs are pretty boring, so you may end up being disappointed.
Using other people's experiences to judge yourself is not a good starting point. Adding mood-altering drugs on top of that, doesn't seem wise.
If you can imagine if drugs didn't exist, would you be happy with your life? If so, there's no reason to let the knowledge of something you don't have affect you negatively that way.
Wait, I thought ecstasy/XTC and MDMA are the same thing?