The solving can be a few times slower on a low end device which you should keep in mind. To aid with this when setting the difficulty for your website it shows you an estimate for various device types. This is indeed a downside of PoW approaches.
There is one factor that helps: you can start solving as soon as the form loads, so as the user enters their details/comment it can start solving - I have a hunch that people on mobile devices are inherently slower at entering their data which should help a bit..
Anyway - if you set the difficulty quite high and the solving takes 30 seconds, it takes the user 15 seconds to enter the form - the user would still have to wait 15 seconds. That's not very different from the time to solve image captchas (it's actually lower and doesn't come with a 2MB payload download which isn't great on phones either, and they can keep their privacy + sanity). You could give the user something to do that makes sense for your website (ask them for feedback?).