The Timing of Evolutionary Transitions Suggests Intelligent Life Is Rare
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The article seems to simply assume the former model ("We assume that once an evolutionary transition is possible (i.e., once the previous transition has occurred), it occurs at a constant average rate λi, so that each ti is exponentially distributed with an expected transition time of βi = 1/λi"), but that feels unjustified to me. Is it really the case that the transition from prokaryote to eukaryote was equally likely at any time, and things simply sat stagnant for a billion years until one day life got lucky?
eg "more likely to find simple life on Mars."
That ape and octopus exist, says that earth didn't win the intelligence lottery, we are watching the long slow grind of compound interest.
When you look at our world we see that the lipid bilayer is preserved, that rna is preserved in every living thing, but eyes have evolved independently many times. That the last common ancestor of octopus and human was a little wriggly thing, leads me to believe that forming a boundary between self and non self is hard (the bilayer), that forming a system of heredity is hard (first rna then dna). That the accumulation of processes that use energy, resources and information from the environment in new ways is a long relentless grind. The basic body form, multicellularity and a gut were, big difficult changes, but maybe intelligence is just paint on a hard won foundation.
https://www.technologyreview.com/2013/04/15/113741/moores-la...
We had to have several generations of stars formed out of the remains of older stars that blew themselves apart, to have more than trace amounts of any element apart from hydrogen and helium.
Earliest you could get rocky planets is probably a couple of billion years after the Big Bang. But more time is better.
In support of this idea, the Cambrian explosion of large (large relative to microbial life) multicellular organisms happened immediately after the 2 billion years of work by blue-green algae had produced enough oxygen into the atmosphere to make larger organisms possible.
https://en.wikipedia.org/wiki/Great_Oxidation_Event
https://www.sciencedaily.com/releases/2010/12/101217145647.h...
I suspect that' gnawing for any research like this. But I could suggest that if we can show that a lot of fundamental changes have come from external shock rather than internal processes, then we might be closer. Further, if the theory of "puncture equilibrium" is true[1], that this would tend to be the case. If we can show that many evolutionary steps involved such external shocks, then we might be closer to this also.
The question would be whether external shocks inevitably produce advances or whether such advances are indeed lucky.
The question is how non-earth world might fail, right.
This looks to me like a hubristic level of extrapolation from a single data point.
The problem has nothing to do with having a nucleus. That's the solution. As you note, it's possible to imagine other solutions. The problem is dealing with gigabytes of genetic data instead of mere megabytes. Typically one would use units of base pairs, but in the context of talking about potential alternative forms of life I'd argue that units of information are more appropriate. In any case, the "easy" strategies suffer from a severe dead end that prevents them from going beyond a few megabytes. Lots of things go wrong at that limit, and while other forms of life would encounter those obstacles in slightly different places, the problem of "simple strategies that don't scale" is almost certainly universal.
https://upload.wikimedia.org/wikipedia/commons/e/e4/Genome_s...
Eukaryotes, in contrast, scale.
It's not an easy task. The strategies are highly elaborate and severely intrusive. They touch the most fundamental, highly conserved aspects of the genome, of cell functionality, and of reproduction. Genes have to be organized hierarchically, packed and unpacked, and everything that interacts with them has to be made compatible with that reality. Further, everything must be done in parallel. The entire architecture of the genome changes as a result. It's like a distributed system vs a monolith. It's a tough, deep-reaching transition to pull off, it's a tougher transition to justify, and that's if you're an engineer capable of things like planning, prediction, and delayed gratification! A greedy optimizer bumbling around in the dark can't rely on cognition (or even a hype cycle!) to propel itself from one mountain range of local optima to another mountain range.
I'm sure there are plenty of strategies for scaling genomes, but if they're all difficult -- and the crazy elaborate mechanisms we see in Earth eukaryotes suggest that could be the case -- then they still constitute a filter.
But yeah, this is all speculation. Nobody really knows.
Energetics and thermodynamics are absolutely capable of imposing harsh boundaries. How long has our battery technology been stuck at this order of magnitude? How long have internal combustion and explosives been stuck at this order of magnitude? A long time, and that's with an enormous number of very clever and motivated people chipping away at the problem.
There's a reason why I chose distributed systems in my analogy: it proves that information science and engineering are not immune to the "difficulty barrier" problem. Vertical scaling hit a soft limit in the software industry long before it enabled the largest cloud-scale applications we see today. The transition from vertical to horizontal scaling was painful, but not nearly as painful as it would have been to wait for vertical scaling to catch up. We'd still be waiting.
This is what I'm talking about. Your making an assumption and straight up saying it's an assumption, but not providing any evidence that this assumption is true. You make another analogy which may or may not apply. I'm not saying you're wrong, and I'm not saying that you're right. I'm saying there is no possible way any of us can know at this point.
The "you can't prove it" objection must be checked at the door for the sake of keeping the speculation interesting. Nobody is arguing that you should walk through the door. It's probably more respectable to refuse, on the whole. Once you walk through the door, though, complaining about proof is a bit silly, like walking into a speakeasy, ordering a drink, and complaining that they have served you illegal alcohol. It's not wrong, but it's also not helpful.
The evolution of eukaryotes is based on the specific path that Earth went down. The combination of RNA, DNA, proteins, and other cellular chemical building blocks are a way that a cell could be constructed, but not the only possible way a cell could be constructed. For an extreme example, we could have non-carbon based life. If that is true, then all of our assumptions about what is scalable and what is not, based on our biochemistry simple cannot be trusted. So, looking at how long it took for something to develop on Earth tells us basically nothing about how long it would take to do that with this other biochemistry.
There is a substantial body of abiogenesis experimentation focused on reproducing DNA/RNA proto-life. They haven't managed to make anything that self-replicates, but they have managed to make nucleic acid polymers with catalytic activity, e.g. you zap the primordial soup with lightning, you get a bunch of short sequences, some of those sequences fold into RNA-zymes that catalytically produce long "AAAAAAAAA" sequences or long repeating "AUAUAUAU" sequences. The critical next step is to demonstrate the ability to do this from a template.
In any case, are you aware of research that aims to do this with alternative polymer chemistries? Such results could inform our speculation about the likelihood of a fundamental 1000x difference.
Likewise if Mars was habitable, you can't adapt to survive there now un less you are a subterranian microbe.
Habitability of planets around red drawfs would of-course change the game, but it's not clear at present.
Eventually they too will become uninhabitable, but the relevant question about alien life is not “eventually” but rather “now”.
I would be pretty unsurprised to find prokaryotic life at least sometimes. I would be much more surprised to find eukaryotes possibly at all, and probably at any high frequency.
If it is engulfment of organelles like mitochondria, that happens all the time. There are fairly good models of the evolutionary tree and how it could happen over time[1].
On the other hand, the ribosome is an amazingly complex machine, which I would expect would be much harder to create. Even synthetically, the path to build a synthetic eukaryote seems a lot easier than the path to build a synthetic ribosome.
Just a bit:
Transcription - https://www.youtube.com/watch?v=SMtWvDbfHLo
Translation - https://www.youtube.com/watch?v=TfYf_rPWUdY
Replication - https://www.youtube.com/watch?v=I9ArIJWYZHI
It's not clear to me how much these features can be degraded without destroying the ability for organisms to reproduce with heritable traits.
Also, when listening to these videos, ask yourself 'how' and 'why' any time an action is described. For example, the following parenthetical questions from a small chunk of the 'Translation' video:
"The addition of each amino acid is a three-step cycle; (Why three step?)
First the tRNA enters the ribosome at the A-Site (Why does it only enter at the A-Site? How are other options prevented and/or made inconsequential? Was it always this way? How did the features of the A-Site evolve for this to happen. What happened before this? ), and is tested for a codon / anti-codon match with the mRNA. (How is the tRNA tested? What happens when it fails the test or is missing the amino acid? What is the energy budget of this test and what are the specific features of the ribosome, RNA, tRNA and amino acid that make it possible? What happened before this testing was done? How did we get from the lack of ability to test and the ability to test?)
Next, provided there is a correct match, the tRNA is shifted to the P-Site (What is the mechanism of this shifting? Why does it only go one direction? What is the energy budget of this process and how is it powered? How do we prevent multiple tRNA from shifting or keep it from shifting more than one spot? What occurred before the ribosome/RNA/tRNA/amino-acid had the features to allow this to occur?)"
You get the idea.
When reasoning from first principals about immune response, it occured to me that just a few simple processes might be all that is required to explore novel active structures in an organism.
Based partly on my understanding of a study of bacteria that evolved the ability to metabolise a new nutrient, a mutation prior to use is required. The ability to detect a molecule might evolve based on immune responses that use random sequences as "test" active sites that are checked for a specific type of deformation.
If this random sequence deforms immediately, it is discarded because this sequence either deforms automatically or deforms in the presence of something common to "host".
If the test remains negative it is released from the host training environment. If the test pattern deforms some time later, it has detected a "foreign" molecule, and has the potential for use as part of a protein that manipulates this molecule.
Recovering the sequence that detects this new foreign molecule becomes the first step in a hereditary immunity. It also stores this useful sequence for possible use in other "testing" systems. These might bring 3 or 4 of these random test systems together to perform another test.
Simple systems that explore a complex space can come up with seemingly elegant solutions.
The most obvious answer to any of your questions is that, if it worked a different way, that's what the video would show... or there would be no video at all.
As for eukaryotes, often, evolution rewards larger size, simply because if you are larger you can't be eaten as easily, you can eat larger prey more easily, etc. Compared to prokaryotes, eukaryotes are gigantic. And they seem to cover the niche of huge lifeforms really well.
I wonder how many early iterations of eukaryote might have actually been smaller, perhaps, if the organism required additional energy sources to support growth.
TL;DR prokaryotes can grow faster due to the structure of their genome. Also, biology doesn’t care what works best, it only cares about what works
And while bigger cells absorbing smaller cells happens all the time, it seems extremely, extremely rare that those events lead to reproducing life. It's probably happened 2X on earth (whatever lead to the original eukaryotes, and the absorption by that lineage of cyanobacteria).
On the other hand, even if had only occurred 2x, ribosomes occurred 1x - all ribosomes are related to each other and didn’t evolve separately.
It's also possible that earlier similar transitions occured but were overwhelmed by the surviving eukaryotic line, whether due to greater metabolic effectiveness, superior repair capabilities, or other factors.
http://hopefullyintersting.blogspot.com/2018/03/the-drake-eq...
The OP twitter thread has a very interesting counterargument to this point in your article:
>Life emerged fairly early on Earth: evidence that it is easy and common? Not so fast: if you need multiple hard steps to evolve an observer to marvel at it, then on those super-rare worlds where observers show up life statistically tend to be early.
At least this does just amplify your conclusion, that intelligent life is more likely to be exceedingly rare rather than die out prematurely.
If this holds, then multicellularity is not at all a hard step from eukaryotes. It's just more of the same.
From a similarly naive viewpoint, once you have evolution, predation, and liminal environments, intelligence is going to be selected for to some degree.[2] It's by no means any kind of saltation.
So one hard step, abiogenesis (maybe-I have doubts about that too).
1. https://en.wikipedia.org/wiki/Symbiogenesis
2. And that's what we have, some degree of intelligence but not much. We can barely understand the input from a few thousand pixels in our foveas (we live about 80 ms in the past), and mostly can't operate our eyes and speech processing centres at the same time.
The fact that human abilities are very limited in some ways supports this. For most evolutionary branches it was a much better strategy to develop excellent eyesight, hearing, running or fighting than to trade off mediocre ones against a sort of general-purpose intelligence and communication skills.
Ten thousands years ago humans didn't seem close to it either and yet they were same as us (and also same as their ancestors for dozens thousands years). 100,000 years is nothing on evolutionary scales and yet during this time our ancestors managed to outcompete other intelligent specie, Neanderthals and probably caused their demise. Considering what our species did to environment it's likely that as long as humans exist, another intelligent species can't evolve here.
And no, as far as anyone has been able to determine, neither birds, whales, dolphins nor apes have anything like a syntactic language, or even our vocabulary.
Octopuses have been around for 500 million years. For most of this time humans were not holding back or inhibiting their propensity to study, receive signals from, send messages to, or travel to, other stars.
But it's not qualitatively different from other species' intelligence. It's just a sample from a distribution, and as such, only a matter of time and speciation.
In the end I am only convinced that the authors' main specialty is grabbing headlines.
[1] from browsing a paper he co-authored with Nick Bostrom, offender #1 of bad probabilistic thinking
It took approximately 4.5 billion years for a series of evolutionary transitions resulting in intelligent life to unfold on Earth. In another billion years, the increasing luminosity of the Sun will make Earth uninhabitable for complex life. Intelligence therefore emerged late in Earth's lifetime. Together with the dispersed timing of key evolutionary transitions and plausible priors, one can conclude that the expected transition times likely exceed the lifetime of Earth, perhaps by many orders of magnitude. In turn, this suggests that intelligent life is likely to be exceptionally rare. Arriving at an alternative conclusion would require either exceptionally conservative priors, finding additional instances of evolutionary transitions, or adopting an alternative model that can explain why evolutionary transitions took so long on Earth without appealing to rare stochastic occurrences. The model provides a number of other testable predictions, including that M dwarf stars are uninhabitable, that many biological paradoxes will remain unsolved without allowing for extremely unlikely events, and that, counterintuitively, we might be slightly more likely to find simple life on Mars."
BTW, the first book that extensively wrote about the basic idea is 20 years old:
"Rare Earth: Why Complex Life Is Uncommon in the Universe" 2000, by Peter Ward, a geologist and evolutionary biologist, and Donald E. Brownlee, a cosmologist and astrobiologist.
https://en.wikipedia.org/wiki/Rare_Earth_(book)
A 20-th anniversary review, covering some details we have learned since then:
https://www.centauri-dreams.org/2020/06/26/a-20th-anniversar...
I think its possible. I think if humans just helped them a little it make take alot less than a million years. It would be cool for Humanity to just foster civilizations in all species on earth. It would really interesting to see how other species's approach to technology.
- have a body that can manipulate tools easily (octopus would fit this)
- have a long enough lifespan to be able to actually learn and discover
- live in an environment that supports primitive metalcasting, mining and agriculture to bootstrap your civilization
When a brain is of sufficient capacity for consciousness to emerge, we can begin to educate these sentients, and teach them all we know, leaving them to figure out how they can apply our knowledge to their perspective of the world, which is alien to us.
Octopus for instance may begin to construct tools that will allow for them to practice aquaculture and build more civilized social structures that move them away from hunter-gatherer lifestyles. When they are not farming, they could develop written language to record their history and debts. Surely if you checked back in tens of thousands of years you would find advanced cities and societies as complex as human ones, except entirely underwater with occasional structures breaking above the surface.
Other creatures like chimpanzees could be taught how to work with humans as a cheap form of labor, digging ditches or mining resources.
https://www.sciencedaily.com/releases/2020/06/200618150301.h...
For a long time, I thought surely these probabilities must basically be zero, due to the sheer amount of dice that can be rolled (tons of space + tons of time), but after hearing a lot of smart people talk about it, I think all of these things do carry a non-zero possibility.
Of course, we'll probably never know, though. There could be some galaxy clusters teeming with life and visible structures but they could be so incredibly far away from us that they basically don't exist from our perspective, and vice versa.
May as well argue about "Civilizations that produce iPhones are rare" - the definition is particular to humans. Monkey-troupe intelligence may indeed be rare, and insectoid emergent reasoning the norm. Or whatever.
That's my point - if we define intelligence as "what humans do" its missing the point. And leaving out a possible universe of intelligent beings.
Something about saying that animals are intelligent triggers some people, specially the "scientist" types.
For example, Koko had an apparent fascination with nipples. In front of cameras, Patterson would always say Koko actually meant something else because nipple rhymes with whatever word she's trying to say but in private, according to other caretakers who worked with Koko, Patterson often showed her nipples to Koko almost like a greeting and made other female workers do the same to their discomfort. She would also ask Koko leading questions to get desired responses for cameras which doesn't demonstrate intelligence.
Patterson apparently also spoiled Koko, feeding her things that weren't good for her nutritionally, but went to great lengths to keep Koko to herself, going so far as to keep her separated from the male they brought in to keep Koko company.
So while I would be excited at the prospect of intelligent animals, I think Koko is unfortunately not a good example.
Uhm, like you do with humans? OK.
She would also ask Koko leading questions to get desired responses for cameras which doesn't demonstrate intelligence.
Like they do in the mainstream news with any other human who is being interviewed? OK.
For example, Koko had an apparent fascination with nipples.
And?
There's no doubt Koko probably understood some things, but not to the complexity that Patterson tried to portray it.
And the thing I was getting at with the nipples was Koko was apparently asking to see people's nipples all the time but in demonstrations Patterson would always play it off like Koko was saying something completely different and more intelligent than it actually was.
https://www.ted.com/talks/freeman_dyson_let_s_look_for_life_...
As for the chance of life, very hard to predict since we only know of our case.
Depends on where your cutoff point of "intelligence" is, we've seen some form of intelligence evolve at least 3 times in birds, mammals and cephalopods. If it's evolved independently 3 times on earth I'd say it's quite likely elsewhere.
Intelligence isn't what separates humans from crows. It's our ability to time bind information past our lifetime. We can use oral traditions, or write down what we have learned. And the next generation doesn't have to start from scratch. And thus you get exponential growth in knowledge.
It is complex language that separates us.
As a data point, it is true some crows have taught their nestlings how to use cars to crack shells to get at the tasty tidbits inside, but that learning doesn't seem to have propagated very far.
Another scenario is that intelligence developed multiple times, but survived long enough to dominate once.
You have an array of hypothetical explanations for the Fermi paradox (mostly drawn from sci-fi. mostly.) to bounce off of all of these estimates and I confess a great curiosity as to which estimates and explanations are true, although it is unlikely that I will ever know.
Still, the silence has tilts me toward the more pessimistic explanations.