I learned the Workman layout. I found it advantageous to do so, but I still don't find this to be a good comparison.

The thing is, no matter which keyboard layout you use, there is the same amount of muscle memory required to be learned.

To contrast, a piano requires 12 times as much muscle memory as a Janko keyboard.

Learning to play a piano is hard, and it is made significantly easier by simply changing the physical keyboard layout.