Thanks to my pursuit, I now give at least 10% of my income to the most cost-effective charities I can find (see GiveWell). Thousands of people do the same: https://www.givingwhatwecan.org/
Many philosophers are working on society's most pressing issues (see the Effective Altruism) movement.
Here's a recent book that may be relevant: https://www.moraluncertainty.com/