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Comment by xiphias2 | Hacker News Reader

COVID is symptomatic, it's a disease. This vaccine is not preventing getting infected, just reduces getting.the disease significantly. I'm more optimistic about Moderna, as this vaccine doesn't prevent me from infecting my parents.

Still, I'll use this vaccine if I can't get Moderna in time. The safety profile looks great.

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> This vaccine is not preventing getting infected, just reduces getting.the disease significantly. I'm more optimistic about Moderna, as this vaccine doesn't prevent me from infecting my parents.

What does that mean? Don't both vaccines work exactly the same? Both are mRNA vaccines.

Moderna's trial protocol collects data to evaluate asymptomatic infections. Pfizer's trial protocol does not.

They have different targets. Moderna stops you from getting infected, BioNTech vaccine stops you from getting sick. mRNA is the delivery technology.

They do the same exact thing.

Not really sure why this is downvoted. SARS-CoV-2 is the virus, COVID-19 is the combination of virus and symptoms.

I can't say anything about these vaccines, but there is such a thing as a non-sterilizing immunity, that would prevent you from developing COVID-19 but still be infected and able to spread SARS-CoV-2.

> This vaccine is not preventing getting infected

What does this mean?

As I understand it, all vaccines ever do is provide you with a prepared immune system for when you do get infected.

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