My observation is that most smart people are very prone to depression if they stop and think about stuff. And yeah, the ongoing global pandemic, social isolation and economical crisis isn’t making that any better.
And that is ignoring all the crap that went down this year and still coming strong.
I would say it actually takes quite a bit of ignorance to ward off semi-constant depression. What helps, I mean properly helps, apart from professional help is frequent physical activity and being in the nature, ideally both combined. Nature has some weird magic effect of recharging some imaginary internal battery and helps you take more life's bullshit and just keep going. Works for literally everybody I know. Covid obviously heavily interferes with both, depending on location.