There's an old joke about golf "The goal of the game is to play as little of it as possible," which is also very true for factorio.
As you advance through the tech tree, previous things you did manually you'll automate more. There's an achievement called "Lazy Bastard" that forces you to do a bare minimum amount of manual work.
One my very first bosses noted the reason he felt I was an exceptional programmer was that I had managed to automate everything at the office from time reporting to doing performance reviews.
I have had some success with certain tasks in the very high-frequency category, but almost no successes with anything that has a cadence higher than a month (always relevant.. https://xkcd.com/1205/)
These were quarterly reviews. Basically I had it copy/paste verbatim the BS from the previous review. This worked for everything except accomplishments. These were 'completed' tasks (from my time reporting) for the reporting period copied into that section.
I wrote weekly status updates, important accomplishments I marked with asterisks. For the annual reviews I just had a script that loaded a TeX template from the past review then populated it from the flagged entries in my weeky reports. Then I'd just edit it down a bit, tweak the language and sent it out. In theory I could have probably gotten away with sending the autogenerated one at least after I'd refined the usage some.
I did it this way because it's always hard to start writing a performance review. But I found it a lot easier to start with a bunch of stuff I did and restrict it down to the relevant stuff.
I was tickled when they later updated the job description for my role and used the text from my performance review. I guess since I didn't have to spend much time populating it I managed to completely optimize the level of corporate-speak in my narrative. :)
In particular, its being able to build a complex distributed system with extremely high visibility to discover the bottlenecks and overflows that need to be resolved. With some Chaos Monkey thrown in as random biter attacks.
...until you start messing with fluid system and oil cracking
for me the only time when I'm always checking the docs is when I'm trying to supply enough water to a nuclear plant. the pressure loss over distance for a pipe almost never matters, but it really does for a nuclear plant. if you don't have a very short run of pipes or lots of pumps along the way, you will never achieve the full potential of your nuclear plant. this can be quite disastrous if you make assumptions about how much power the plant will make. I wish they would add something to the UI to make it a bit more clear when pipe runs are too long.