My friends brother runs a landscaping business, purely off his iphone. He asked me for advice on how to get his iphone onto a laptop, like with an emulator or something. This was about a year ago, so the ARM mac stuff was just rumors at that stage, and I mentioned that it wasnt possible.
Now, I can say hey if you get one of the new macbooks / mac minis, you can run your iphone apps natively. He probably will be one of their first customers.
I wouldnt be surprised if there was a huge 'professional' market that is untapped. not the traditional professional market but the ones which want something as simple & familiar as a iphone, on a desktop.