Running uBlock Origin [1] and NextDNS [2], I can't remember when I last saw an ad on YouTube. I recommend you give it a try.
I recommend going with the APK version of NewPipe as the FDroid install often takes a while to catch up to breaking changes on youtube.
https://archive.newpipe.net/fdroid/repo?fingerprint=E2402C78...
However, neither Adguard nor DNS based blocking will block ads in the iOS Youtube App.
Vanced is a modded YT app, while NewPipe is open source and has a background player too, with download feature.