From the fine article:
>We evaluated the impact of 3 months of IF (12, 16, and 24 hr of food deprivation on a daily basis)
>We evaluated the impact of 3 months of IF (12, 16, and 24 hr of food deprivation on a daily basis)
We were upstairs when we realized it was the first ice cold night of the year.
So we went down and mice are cuddled in the cold , and apparently out of food.
Someone decided fruit loops mixed in with mouse food was a good idea. One mouse went and ate. Other one was clearly in roughed shap.
First mouse took a fruit loop, walked it over, and kept putting it against the others mouth. After couple minutes she started eating.
The sheer empathy of one mouse helping another still gets to me.
They both were fine after eating and being moved to a warm spot.
For those interested here is a great interview with David Sinclair, Harvard Researcher on aging:
I'm not against doing these kinds of studies on mice but the only conclusion you can really get is that we should do longer studies on animals that are closer to humans or on humans themselves.
Most probably, weight loss will be less than pound in water calorie restriction.
Also, there was studies on Ramadan fasting and they've found almost two fold increase of serum brain-derived neurotrophic factor at the end of fast. Level of BDNF correlates with neuroneogenesis in brain.
12 is better than, say, 8 or 6 (e.g., snacking at night).
Curious how your experience compares to your pre-IF state 5+yrs ago?
BMI 18-19 for reference.
Would you mind sharing your BMI from before IF? Also curious if you feel IF is better than the alternatives (e.g., Keto, which for me has been the "easiest" of the effective diets)
I did have a really good experience doing long fasted running in the morning. At first I couldn't go three miles without breakfast. But eventually I could do twelve straight out of bed and feel great.
As I understand, fasting trains your body to supply blood glucose from fat stores, which breaks your brain's craving for sugary foods- which are a crutch for getting your blood sugar up. (Remember, your brain runs mainly on blood glucose)
Keto does the same thing a different way. But to me IF is way easier and healthier. (I strive to eat a Mediterranean style diet which ain't Keto!)
I would say the experience for me is really good- as long as I avoid the cliff, which is what I was warning about. Basically, just don't try to get all extreme thinking longer fasts are always better.
Stay up all night playing factorio. No food, of course, because you're in a middle of a refactor and you can't be bothered to eat. Crash in the afternoon and sleep until midnight. There you go, easy mode health++, apparently.
Generally for health you aim for a longer fast with perhaps social break nights. But whatever works.
Sadly, leap seconds are rare.
given different metabolism speed and body energy stores depletion rate that would translate into days for humans.
Sidenote: it is not a good thing to torture animals.