This is what worked your someone I knew. YMMV.

1. Introduce him to one of many free online UI/UX courses and figure out if he's actually into it. If he isn't, try some other tech thing.

2. Once you've figured out what he's into, make him do one or two online courses in it, preferable from a good university (see: edx.org).

3. Work on a portfolio. Projects of his own, and contributions to F/OSS projects.

4. Add more to the portfolio. Non-profits often will give people with little previous experience a chance.

5. Apply to jobs for a junior position. Try small companies if he isn't having success elsewhere.

6. If he's finding it impossible to find work, internships are the way to go. They often make it easier to get jobs.