Indeed, I think this post ends up being a good argument against Lisp. The supposed negative for JS, as opposed to Lisp, is that "We’d need something like Babel to parse our file, and work on top of the AST to make sure we rewrite our code safely." And? Computers are good at parsing, and adding syntax to a language should be comparatively rare, so why would I choose a language that optimizes for this case, rather than one which optimizes for human readability?

I think some people will argue that macros shouldn't be rare, that you should define a custom DSL for each application so you can work at a higher level of abstraction. However, macros themselves operate at a fairly low level of abstraction (operating on the AST, rather than closer to the problem domain). I would argue that if you find yourself using macros frequently, that's a sign your language is lacking in higher-level abstraction capabilities.