How much is a normal dose of LSD, for reference?
That said, the short-term tolerance curve is incredibly steep. What ends up happening with a lot of folks who microdose for extended periods is that they'll increase the 'micro' until they make a rounding error and then all of a sudden your desk is melting and your mouse has a half-minute delay. Best practices are to stagger days and take occasional three-to-four day long breaks.