That seems a bit much, but I do feel bad for anyone named Karen now that it's become a meme. It seems really insensitive to turn a person's name into a pejorative.
There are countless other examples in English and other languages. Amazon coopted Alexa. Apple, siri. I've met more than one person named Isis.
Unfortunately language is still a rough tool. We name things from mathematical proofs, to sea slugs, or even groups of people with certain identifiable characteristics, arbitrarily and sometimes capriciously.
Ultimately those effected find a way to adapt to an environment that's coopted one of their identifiers under a new definition in the collective lexicon. Trying to fight it usually just makes things worse.