This is another in the "Now that we have computers with gazillions of bits of RAM and many cores and gazillions of cycles, what conventional wisdom is no longer wise?" series :-).
I suggested to a client that they use Sqlite3 for their company database rather than a disk based database. And they looked at me shocked, as if I had spoken heresy. I pointed out how many records they could store on a 64GB machine and that is a small data center class machine and it sort of boggled their mind. Add read-only copies, shared from a NAS device gave them perfect scalability in terms of queries per second (their sales folks had their own database that they were updating). It was fun to watch their expression go from horror to wonder to excitement when they finally implemented it.